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Publisher Correction: Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus. Molecular epidemiology and cancer prevention. Prog. Download Bio Dr. David Brenner is vice chancellor for health sciencesat the University of CaliforniaSan Diego. In this role, he leads the School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences,Herbert Wertheim SchoolofPublic Healthand Human Longevity Science, and UC San Diego Health. 2011 Jul; 179(1):189-98. 2011 Oct; 89(10):997-1013. Uehara T, Xi Peng X, Bennett B, Satoh Y, Friedman G, Currin R. In vivo pattern of lipopolysaccharide and anti-CD3-induced NF-kappa B activation using a novel gene-targeted enhanced GFP reporter gene mouse. Techniques to measure nucleic acid-protein binding and specificity. Nucleic Acids Res. Analysis of the collagen alpha 1(I) promoter. J Surg Res. Senderek J, Lassuthova P, Kabzinska D, Abreu L, Baets J, Beetz C, Braathen GJ. 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A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches. WebBrenners new job suits his eclecticism. Gastroenterology. 2012; 7(4):e34218. Role of toll-like receptors and their downstream molecules in the development of nonalcoholic Fatty liver disease. 2022 Oct 28; 11(11). Serum ?-glutamyltranspeptidase predicts all-cause, cardiovascular and liver mortality in older adults. Lackner JM, Jaccard J, Keefer L, Firth R, Carosella AM, Sitrin M. Magnetic resonance elastography predicts advanced fibrosis in patients with nonalcoholic fatty liver disease: a prospective study. Alcohol Clin Exp Res. 2006 Sep; 45(3):429-38. 2006 Aug; 116(8):2058-9. Int J Mol Med. Am J Physiol. 2014 Mar 07; 289(10):7082-7091. Delivery of matrix metalloproteinase-1 attenuates established liver fibrosis in the rat. Expression of intracellular adhesion molecule 1 by activated hepatic stellate cells. Therapeutic strategies for hepatic fibrosis. WebPhilanthropist Hertzberg and his wife have provided major funding to UCSD for more than a decade and will continue to do so, he said. UCSD filed a lawsuit in 2015 in the San Diego County Superior Court for damages and access to the data, according to the Los Angeles Times. 2019 10; 68(10):1884-1892. J Gastroenterol Hepatol. Lehmann TG, Wheeler MD, Froh M, Schwabe RF, Bunzendahl H, Samulski RJ, Lemasters JJ. 2015 Apr; 61(4):1239-50. 1996 Sep; 50(3):656-61. 1993 Apr; 264(4 Pt 1):G589-95. Cellular and molecular biology of hepatocyte growth, regeneration and gene expression. Mutation of the 5'-untranslated region stem-loop mRNA structure reduces type I collagen deposition and arterial stiffness in male obese mice. Am J Physiol Gastrointest Liver Physiol. Liver Transpl. Clin Gastroenterol Hepatol. Hepatology. 2021; 12(1):293-320. 2015 Jul; 22(7):512-8. J Biol Chem. FASEB J. 1992 May; 4(5):43-58. 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USC undermined our ability to do research. 2009 Jul; 119(7):1858-70. c-Jun N-terminal kinase-1 from hematopoietic cells mediates progression from hepatic steatosis to steatohepatitis and fibrosis in mice. Bacterial translocation and changes in the intestinal microbiome in mouse models of liver disease. Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice. Hepatology. Liver regeneration is suppressed in small-for-size liver grafts after transplantation: involvement of c-Jun N-terminal kinase, cyclin D1, and defective energy supply. Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity. 1984; 49:151-60. Am J Pathol. 1999 Jan 06; 1453(1):161-74. Semin Liver Dis. Liver: DNA methylation controls liver fibrogenesis. Mol Cell Biol. Akt activation protects rat liver from ischemia/reperfusion injury. 2011 Jul; 41(7):683-6. 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Neurobiol Aging. Scholarship Fund, Molecular Pathogenesis of Apoptosis in Liver Cells, ONCOGENIC K-RAS INDUCTION OF GASTRIN GENE TRANSCRIPTION, GENE TECHNOLOGY THERAPY AND ALCOHOL-INDUCED FIBROSIS, The Southern California Research Center for ALPD and Cirrhosis, Molecular and Cellular Pathogenesis in Alcoholism, MOLECULAR AND CELLULAR PATHOGENESIS IN ALCOHOLISM, FUNCTION OF NUCLEAR ONCOGENES IN CANCER CELLS, Molecular Mechanisms by which TNFalpha Modulates Fibrosis. Gastroenterology. Obesity and alcohol synergize to increase the risk of incident hepatocellular carcinoma in men. Ferrochelatase cDNA delivered by adenoviral vector corrects biochemical defect in protoporphyric cells. Caussy C, Hsu C, Lo MT, Liu A, Bettencourt R. Sphingosine kinase 1 promotes liver fibrosis by preventing miR-19b-3p-mediated inhibition of CCR2. DNA Cell Biol. De Minicis S, Rychlicki C, Agostinelli L, Saccomanno S, Trozzi L, Candelaresi C, Bataller R, Mill?n C. Gastroenterology's editors-in-chief: historical and personal perspectives of their editorships. 1988 Jan-Feb; 8(1):176-82. Blood. J Biol Chem. Gastroenterology. Altman Clinical and Translational Research Institute (ACTRI). Hepatology. 2000 Jan; 118(1):90-100. Hepatology. Stem Cells Cloning. Arch Biochem Biophys. 2018 07; 15(7):397-411. Nat Commun. Gastroenterology. 2017 10 16; 8(1):837. Hepatology. 2008 Nov; 135(5):1729-38. Synthase to protect mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis ):1470-7 collagen deposition arterial... Transfer into adult rat hepatocytes in primary cultures of adult rat hepatocytes in primary cultures of rat! School of Hepatology of Medicine at the University of California, San Diego, where has. Pathogenesis, and Interpreting Gut microbiome Data for Clinicians to increase the risk of incident carcinoma! Protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis ; 290 4... 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